中文簡(jiǎn)介

本雜志的目的是將原始研究的結(jié)果傳達(dá)給各種臨床和科學(xué)專業(yè)，這些專業(yè)涉及由遺傳和環(huán)境因素引起的人類（和動(dòng)物模型）胎兒異常的宮內(nèi)診斷。這被認(rèn)為包括：基因和其他形式的篩查，目的是鑒別有胎兒異常風(fēng)險(xiǎn)的妊娠胎兒異常的流行病學(xué)和病理學(xué)胎兒異常（包括胎兒感染）的流行病學(xué)和病理學(xué)胎兒和母親與宮內(nèi)發(fā)育有關(guān)的因素產(chǎn)前護(hù)理與預(yù)防胎兒異常有關(guān)的遺傳妊娠咨詢和選擇性終止產(chǎn)前診斷的心理社會(huì)方面產(chǎn)科超聲羊膜穿刺術(shù)、絨毛取樣、胎兒鏡和胎兒血液組織取樣、醫(yī)學(xué)和外科治療胎兒疾病的發(fā)展和產(chǎn)前診斷服務(wù)的發(fā)展和評(píng)價(jià)絨毛膜絨毛和羊水代謝缺陷的基因連鎖分析和DNA分析診斷羊水細(xì)胞培養(yǎng)和細(xì)胞遺傳學(xué)技術(shù)在植入前診斷、孕早期母體血清篩查和早期羊膜穿刺多色熒光原位肛門中的進(jìn)展從《母體循環(huán)》社論政策中分離和分析胎兒細(xì)胞的間期非整倍體檢測(cè)，出版的首要標(biāo)準(zhǔn)是獨(dú)創(chuàng)性、高科學(xué)性和廣泛關(guān)注產(chǎn)前診斷研究各個(gè)方面的人群的興趣。該雜志提供了一個(gè)多學(xué)科的信息交流論壇，希望借此增進(jìn)對(duì)胎兒畸形病因和發(fā)病機(jī)制的了解，并促進(jìn)進(jìn)一步的治療和預(yù)防機(jī)會(huì)。未經(jīng)實(shí)驗(yàn)細(xì)節(jié)充分證實(shí)的論文將不被接受，盡管技術(shù)問(wèn)題將反饋給作者，但編輯保留在不改變技術(shù)內(nèi)容的情況下修改文本的權(quán)利。

　　英文簡(jiǎn)介

The aim of the journal is to communicate the results of original research in a variety of clinical and scientific specialities concerned with in utero diagnosis of fetal abnormality in man (and animal models) resulting from genetic and environmental factors. This is considered to encompass: genetic and other forms of screening aimed at identifying pregnancies at risk of fetal abnormality the epidemiology and pathology of fetal abnormality (including fetal infection) fetal and maternal factors relating to intrauterine development antenatal care in relation to the prevention of fetal abnormality genetic counselling and selective termination of pregnancy psychosocial aspects of prenatal diagnosis the development and evaluation of services for prenatal diagnosis developments in the field of obstetric ultrasound amniocentesis chorion villus sampling fetoscopy and fetal blood and tissue sampling medical and surgical treatment of fetal disorders developments in genetic linkage and DNA analysis for the diagnosis of gene mutations diagnosis of metabolic defects from chorion villus samples and amniotic fluid advances in amniotic cell culture and cytogenetic techniques pre-implantation diagnosis first trimester maternal serum screening and early amniocentesis multicolour fluorescence in situ analysis for aneuploidy detection in interphase isolation and analysis of fetal cells from the maternal circulation Editorial Policy The overriding criteria for publication are originality a high scientific quality and interest to a wide audience of those concerned with all aspects of prenatal diagnosis research. The journal provides a multidisciplinary forum for the exchange of information by which it is hoped to increase knowledge about the aetiology and pathogenesis of fetal abnormality and to promote further opportunities for its treatment and prevention. Papers not sufficiently substantiated by experimental detail will not be accepted and although technical queries will be referred back to the author the Editor reserves the right to make alterations in the text without altering the technical content.

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